N-Fmoc-D-valine

CAS: 84624-17-9

Ref. TR-F680005

Product Information

• Name: N-Fmoc-D-valine
• Synonyms: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-valine, (R)-N-Fmoc-valine, 289: PN: US20070042401 PAGE: 37 Claimed Protein, 980: PN: WO2006135786 PAGE: 70 Claimed Protein, D-Fmoc-Valine, N-(9-Fluorenylmethoxycarbonyl)-D-valine, N-(9-fluorenylmethoxycarbonyl)-D-valine, Fmoc-D-Val-OH, NALPHA-9-Fluorenylmethoxycarbonyl-D-valine

Description

Applications N-Fmoc-D-valine is an N-Fmoc-protected form of D-Valine (V094200). D-Valine (an isomer of the essential amino acid L-Valine [V094205])exhibited inhibitory effects on fibroblasts that contaminated mammalian kidney cultures, allowing for selective growth epithelial cells. D-Valine is also known for its presence in the structure of Actinomycin D, an antitumour drug. D-Valine is naturally synthesized by Streptomyces antibioticus.
References Chu, W., et al.: J. Am. Chem. Soc., 116, 7971 (1994); Gilbert, S & Migeon, B.: J. Cell. Phys., 92, 161 (1977); Salzman, L., et al.: J. Biol. Chem., 239, 1864 (1964); Sordillo, L., et al.: Cell Biol. Int. Rep., 12, 355 (1988)

• Brand: TRC

Chemical properties

• Molecular weight: 339.39
• Formula: C₂₀H₂₁NO₄
• Color/Form: Neat
• InChI: InChI=1S/C28H44O3/c1-18(2)28(6,31)15-13-19(3)24-11-12-25-21(8-7-14-27(24,25)5)9-10-22-16-23(29)17-26(30)20(22)4/h9-10,13,15,18-19,23-26,29-31H,4,7-8,11-12,14,16-17H2,1-3,5-6H3/b15-13+,21-9+,22-10-/t19-,23-,24-,25+,26+,27-,28?/m1/s1
• InChI key: InChIKey=ODZFJAXAEXQSKL-GNMODTJUSA-N
• SMILES: C=C1/C(=C\C=C2/CCC[C@@]3(C)[C@H]2CC[C@@H]3[C@H](C)/C=C/C(C)(O)C(C)C)C[C@@H](O)C[C@@H]1O