N-Formyl Leurosine(>85%)

CAS: 54022-49-0

Ref. TR-F700650

Product Information

• Name: N-Formyl Leurosine(>85%)
• Synonyms: (3'α,4'α)-4'-Deoxy-3',4'-epoxy-22-oxovincaleukoblastine, 22-Oxoleurosine, F-Leurosine, Formylleurosine, Leuroformine, N-Demethyl-N-formylleurosine, N-Formyl N-demethylleurosine, NSC 269419, Vinformide, Vincristine Impurity G, (2alpha,2'beta,3alpha,3'beta,4alpha,5beta,19beta)-22-oxo-O~3~',3'-cyclovincaleukoblastine, 1H-Indolizino[8,1-cd]carbazole, vincaleukoblastine deriv., 22-oxo-O~3~',3'-cyclovincaleukoblastine, 2H-3,13-Methanooxireno[9,10]azacycloundecino[5,4-b]indole, vincaleukoblastine deriv., 4'-Desoxy-3'alpha,4'alpha-epoxyvincristin, Formyl-leurosine, N-Formylleurosine, Nsc 269419, Unii-I4U9Nzs9T5, Vincaleukoblastine, 4'-deoxy-3',4'-epoxy-22-oxo-, (3'-alpha,4'-alpha)- (9CI), Vincaleukoblastine, 4′-deoxy-3′,4′-epoxy-22-oxo-, (3′α,4′α)-, Vinformida, Vinformida [INN-Spanish], Vinformide [INN], Vinformidum, Vinformidum [INN-Latin], f-Leu

Description

Impurity Vincristine Impurity G
Stability Hygroscopic
Applications Degradation products of Vincristine. A Vinca dimer, a potent cytostatic agent. Vincristine Impurity G.
References Erdelyi-Toth, V., et al.: Eur. J. Cancer, 17, 329 (1981), Ronai-Lukacs S; Eur. J. Drug Metab. Pharmacokinet., 7, 4 (1982),

• Brand: TRC

Chemical properties

• Molecular weight: 822.94
• Formula: C₄₆H₅₄N₄O₁₀
• Purity: >85%
• Color/Form: Neat
• InChI: InChI=1S/C46H54N4O10/c1-7-42-15-11-17-49-19-16-44(37(42)49)30-20-31(34(56-4)21-33(30)50(25-51)38(44)46(55,41(54)58-6)39(42)59-26(3)52)45(40(53)57-5)22-27-23-48(24-43(8-2)36(27)60-43)18-14-29-28-12-9-10-13-32(28)47-35(29)45/h9-13,15,20-21,25,27,36-39,47,55H,7-8,14,16-19,22-24H2,1-6H3/t27-,36-,37?,38+,39+,42+,43+,44+,45-,46-/m0/s1
• SMILES: CC[C@@]12C=CCN3CC[C@]4(c5cc([C@]6(C(=O)OC)C[C@H]7C[N@@](CCc8c6[nH]c6ccccc86)C[C@@]6(CC)O[C@H]76)c(OC)cc5N(C=O)[C@H]4C(O)(C(=O)OC)[C@@H]1OC(C)=O)[C@@H]32