10-Formyl-5,6,7,8-tetrahydro Folic Acid Disodium (Technical Grade)

CAS: 914800-65-0

Ref. TR-F701095

Product Information

• Name: 10-Formyl-5,6,7,8-tetrahydro Folic Acid Disodium (Technical Grade)
• Synonyms: N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-L-Glutamic Acid Disodium
• Brand: TRC
• Description: Stability Hygroscopic, Light Sensitive, Temperature SensitiveApplications 10-Formyl-5,6,7,8-tetrahydro Folic Acid Disodium Salt is the disodium salt of F701085, which is a Folic Acid (F680300) derivative. Folic Acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.10-Formyl-5,6,7,8-tetrahydro Folic Acid Disodium Salt is also used in the diagnosis and prevention and therapy of cerebral folate dificiency in relation to formation of folate receptor autoantibodies and treatment with reduced folate and antioxidants.References Slieker, L.J., et al.: Mol. Pharmacol., 25, 294-302 (1984); Xu, L., et al.: Mol. Pharm., 7, 1311 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010); Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010); McKay, D., et al.: Nut. J., 9 (2010)Ramaekers, WO 2006119589, (2006)

Chemical properties

• Molecular weight: 517.4
• Formula: C₂₀H₂₁N₇Na₂O₇
• Color/Form: Neat
• InChI: InChI=1S/C20H23N7O7.2Na/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30;;/h1-4,9,11,13,23H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,22,25,26,32);;/q;2*+1/p-2/t11?,13-;;/m0../s1
• InChI key: InChIKey=YAAHOQFUMOTHOP-RNVQNLIPSA-L
• SMILES: Nc1nc(=O)c2c([nH]1)NCC(CN(C=O)c1ccc(C(=O)N[C@H](CCC(=O)O[Na])C(=O)O[Na])cc1)N2