Fosfomycin Tromethamine

CAS: 78964-85-9

Ref. TR-F727505

Product Information

• Name: Fosfomycin Tromethamine
• Synonyms: Fosfomycin trometamol, 2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrogen (2R,3S)-(3-methyloxiran-2-yl)phosphonate, Phosphonic acid, P-[(2R,3S)-3-methyl-2-oxiranyl]-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (2R-cis)-(3-methyloxiranyl)phosphonate (1:1) (salt), 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, [(2R,3S)-3-methyloxiranyl]phosphonate (1:1) (salt), 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium hydrogen [(2R,3S)-3-methyloxiran-2-yl]phosphonate, Fosfomycin Trometamol, Fosfomycin compd. with trometamol, Fosfomycin trometamol salt, Fosfotricin, Monuril, Monurol, Monurol Sachet, Phosphonic acid, (3-methyloxiranyl)-, (2R-cis)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), Phosphonic acid, P-[(2R,3S)-3-methyl-2-oxiranyl]-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), Phosphonomycin monotrometamol, Tromethamine-fosfomycin, Z 1282, [(2S,3R)-3-methyloxiran-2-yl]phosphonic acid - 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)

Description

Stability Hygroscopic
Applications Fosfomycin Tromethamine is used as an antibiotic compound in the treatment of urinary tract infections.
References Keating, G. et al.: Drugs, 73, 1951 (2013); Demir, T. et al.: Int. J. Infect. Dis., 17, e966 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 259.19
• Formula: C₄H₁₁NO₃·C₃H₇O₄P
• Color/Form: Neat
• InChI: InChI=1S/C4H11NO3.C3H7O4P/c5-4(1-6,2-7)3-8;1-2-3(7-2)8(4,5)6/h6-8H,1-3,5H2;2-3H,1H3,(H2,4,5,6)/t;2-,3+/m.0/s1
• InChI key: InChIKey=QZJIMDIBFFHQDW-LMLSDSMGSA-N
• SMILES: C[C@@H]1O[C@@H]1P(=O)(O)O.NC(CO)(CO)CO