Fosinopril Sodium Salt

CAS: 88889-14-9

Ref. TR-F727800

Product Information

• Name: Fosinopril Sodium Salt
• Synonyms: (4S)-4-Cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline, sodium salt, [1[S*(R*)],2alpha,4beta]-4-Cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline, sodium salt, Acecor, Eosinopril, Fosinopril sodium, Monopril, SQ 28555, Secorvas, Staril, (4S)-4-Cyclohexyl-1-{[(RS)-2-methyl-1-(propionyloxy)propoxy]-(4-phenylbutyl)phosphinylacetyl}-L-proline sodium salt, (4S)-4-cyclohexyl-1-{[(R)-[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl}-L-proline, (4S)-4-cyclohexyl-1-{[{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}-L-proline, <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt (1:1), (4S)-, <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-, <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, [1[S*(R*)],2α,4β]-, Fosenopril sodium, Sq 28555, sodium (2S,4S)-4-cyclohexyl-1-({[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate, sodium (2S,4S)-4-cyclohexyl-1-{[(R)-{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylate

Description

Applications A phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
References Singhvi, S.M., et al.: Br. J. Clin. Pharmacol., 25, 9 (1988), Sullivan, P.A., et al.: Am. J. Hypertension, 1, 280S (1988),

• Brand: TRC

Chemical properties

• Molecular weight: 585.64
• Formula: C₃₀H₄₅NO₇P·Na
• Color/Form: Neat
• InChI: /q, +1/p-1/t25-,26+,30-,39-, InChI=1S/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24, /m1./s1, /h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35)
• InChI key: InChIKey=TVTJZMHAIQQZTL-OOSVCYLOSA-M
• SMILES: CCC(=O)O[C@@H](O[P@](=O)(CCCCc1ccccc1)CC(=O)N1C[C@@H](C2CCCCC2)C[C@@H]1C(=O)O[Na])C(C)C