2-Furoylglycine-d3

CAS: 5657-19-2

Ref. TR-F865227

Product Information

• Name: 2-Furoylglycine-d3
• Synonyms: 2-[(3,4,5-trideuteriofuran-2-carbonyl)amino]acetic acid, (2Z)-2-[(2-methylphenyl)hydrazono]-1-benzothiophen-3(2H)-one, 2-(2-Furoylamino)acetic acid, 2-(Furan-2-ylformamido)acetic acid, 2-Furancarboxamide, N-(carboxymethyl)-, 2-Furoylglycine, 2-[(Furan-2-carbonyl)amino]acetic acid, 2-[(Furan-2-yl)formamido]acetic acid, Brn 0142378, Furfuroylglycine, Furoilglicina, Furoilglicina [Italian], Furoylglycine, Glycine, N-(2-furanylcarbonyl)-, Glycine, N-(2-furanylcarbonyl)- (9CI), Glycine, N-2-furoyl-, N-(2-Furanylcarbonyl)glycine, N-(furan-2-ylcarbonyl)glycine, Pyromucuric acid, [(Furan-2-carbonyl)amino]acetic acid, [[(Furan-2-yl)carbonyl]amino]acetic acid

Description

Applications 2-Furoylglycine-d3 is the isotope labelled analog of 2-Furoylglycine (F865225); an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolylazabicyclooctylethylpiperidines as Ccr5 antagonists for the treatment of HIV infection.
References Antonysamy, S., et al.: Bioorg. Med. Chem. Lett., 18, 2990 (2008); Kazmierski, W., et al.: PCT Int. Appl. (2004), WO 2004054974 A2 20040701

• Brand: TRC

Chemical properties

• Molecular weight: 172.15
• Formula: C₇D₃H₄NO₄
• Color/Form: Neat
• InChI: InChI=1S/C7H7NO4/c9-6(10)4-8-7(11)5-2-1-3-12-5/h1-3H,4H2,(H,8,11)(H,9,10)/i1D,2D,3D
• InChI key: InChIKey=KSPQDMRTZZYQLM-CBYSEHNBSA-N
• SMILES: [2H]c1oc(C(=O)NCC(=O)O)c([2H])c1[2H]