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(S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride
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(S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride

CAS: 925902-48-3

Ref. TR-F925905

100mg
1,588.00 €
Estimated delivery in United States, on Friday 30 Aug 2024

Product Information

Name:
(S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride
Controlled Product
Synonyms:
  • 2-methylpropoxycarbonyl (2S)-2-(3-fluoro-4-phenylphenyl)propanoate
Description:

Applications (S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride is an intermediate in the synthesis of Rimacalib (R505015), an inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib.
References Westra, Johanna., et al.: BMC Musculoskelet Disord.,11 , No pp. given. (2010);

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
344.377
Formula:
C20H21FO4
Color/Form:
Neat
InChI:
InChI=1S/C20H21FO4/c1-13(2)12-24-20(23)25-19(22)14(3)16-9-10-17(18(21)11-16)15-7-5-4-6-8-15/h4-11,13-14H,12H2,1-3H3/t14-/m0/s1
InChI key:
InChIKey=WAYFJZACBWHVSA-AWEZNQCLSA-N
SMILES:
CC(C)COC(=O)OC(=O)[C@@H](C)c1ccc(-c2ccccc2)c(F)c1
MDL:
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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