![(S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FF925905.webp&w=3840&q=75)
(S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride
CAS:
Ref. TR-F925905
100mg
1,530.00€
Product Information
Name:(S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride
Controlled Product
Synonyms:
- 2-methylpropoxycarbonyl (2S)-2-(3-fluoro-4-phenylphenyl)propanoate
Brand:TRC
Description:Applications (S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic (Isobutyl Carbonic) Anhydride is an intermediate in the synthesis of Rimacalib (R505015), an inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib.References Westra, Johanna., et al.: BMC Musculoskelet Disord.,11 , No pp. given. (2010);
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Chemical properties
Molecular weight:344.377
Formula:C20H21FO4
Color/Form:Neat
InChI:InChI=1S/C20H21FO4/c1-13(2)12-24-20(23)25-19(22)14(3)16-9-10-17(18(21)11-16)15-7-5-4-6-8-15/h4-11,13-14H,12H2,1-3H3/t14-/m0/s1
InChI key:InChIKey=WAYFJZACBWHVSA-AWEZNQCLSA-N
SMILES:CC(C)COC(=O)OC(=O)[C@@H](C)c1ccc(-c2ccccc2)c(F)c1
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