Product Information
Name:Gefitinib Morpholine N-oxide
Controlled Product
Synonyms:
- 4-Quinazolinamine
- N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-oxido-4-morpholinyl)propoxy]-
- Gefitinib N-Oxide
- N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-oxido-4-morpholinyl)propoxy]-4-quinazolinamine
Brand:TRC
Description:Applications Gefitinib Morpholine N-oxide is the N-oxide derivative of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).References Lynch, T.J., et al.: N. Engl. J. Med., 350, 2129 (2004); Engelman, J.A., et al.: Science, 316, 1039 (2007); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:462.90
Formula:C22H24ClFN4O4
Color/Form:White To Off-White
InChI:InChI=1S/C22H24ClFN4O4/c1-30-20-13-19-16(12-21(20)32-8-2-5-28(29)6-9-31-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
InChI key:InChIKey=FIKOGZWCACSBHA-UHFFFAOYSA-N
SMILES:COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCC[N+]1([O-])CCOCC1
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