Gemfibrozil 1-O-b-D-(3,4,5-O-Triacetyl)glucuronide

Ref. TR-G305780

Product Information

• Name: Gemfibrozil 1-O-b-D-(3,4,5-O-Triacetyl)glucuronide
• Synonyms: 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] β-D-(3,4,5-O-Triacetyl)glucopyranuroic Acid
• Brand: TRC
• Description: Applications Gemfibrozil 1-O-β-D-(3,4,5-O-Triacetyl)glucuronide is an intermediate for the synthesis of Gemfibrozil 1-O-β-Glucuronide (G305755), which is the pure form of Gemfibrozil 1-O-β-Glucuronide (contains up to 15% α isomer) (G305760), and it is the major metabolite of Gemfibrozil. Gemfibrozil is a serum lipid regulating agent used as an antihyperlipoproteinemic.References Kissebach, A.H., et al.: Atherosclerosis, 24, 199 (1976); Lewis, J.E., et al.: Pract. Cardiol., 9, 99 (1983); Rubins, H.B., et al.: N. Engl. J. Med., 341, 410 (1999)

Chemical properties

• Molecular weight: 552.57
• Formula: C₂₇H₃₆O₁₂
• Color/Form: Neat
• InChI: InChI=1S/C27H36O12/c1-14-9-10-15(2)19(13-14)34-12-8-11-27(6,7)26(33)39-25-23(37-18(5)30)21(36-17(4)29)20(35-16(3)28)22(38-25)24(31)32/h9-10,13,20-23,25H,8,11-12H2,1-7H3,(H,31,32)/t20-,21-,22-,23+,25-/m0/s1
• InChI key: InChIKey=QFGGRIDJZAGQKH-WHGMEAMLSA-N
• SMILES: CC(=O)O[C@@H]1[C@@H](C(=O)O)O[C@@H](OC(=O)C(C)(C)CCCOc2cc(C)ccc2C)[C@H](OC(C)=O)[C@H]1OC(C)=O