Product Information
- 4H-1-Benzopyran-4-one
- 3-[4-(β-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-
- Sophoricoside (6CI,7CI,8CI)
- 3-[4-(β-D-Glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
- 4',5,7-Trihydroxyisoflavone 4'-β-D-glucopyranoside
- 5',7'-Dihydroxy-4'-glucosyloxyisoflavone
- Genistein 4'-O-glucoside
- Genistein
- 4'-β-D-glucopyranoside
- 3-[4-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
- See more synonyms
- 4-(5,7-dihydroxy-4-oxo-4H-chromen-3-yl)phenyl alpha-L-gulopyranoside
- 4-(5,7-dihydroxy-4-oxo-4H-chromen-3-yl)phenyl beta-D-glucopyranoside
- 4H-1-Benzopyran-4-one, 3-[4-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)phenyl]-5,7-dihydroxy-
- 4′,5,7-Trihydroxyisoflavone 4′-β-<span class="text-smallcaps">D</span>-glucopyranoside
- 5′,7′-Dihydroxy-4′-glucosyloxyisoflavone
- Genistein 4′-O-glucoside
- Genistein, 4′-β-<span class="text-smallcaps">D</span>-glucopyranoside
- Sophoricoside
Applications Genistein 4'-β-D-glucopyranoside is a metabolite of Genistein (G350000), which exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation.
References Akiyama, T., et al.: J. Biol. Chem., 262, 5592 (1987), O'Dell, T.J., et al.: Nature, 353, 588 (1991), Aharonovits, O., et al.: Biochim Biophys. Acta, 1112, 181 (1992), Platanias, L.C., et al.: J. Biol. Chem., 267, 24053 (1992),
Chemical properties
Technical inquiry about: TR-G349975 Genistein 4'-b-D-glucopyranoside
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