Ginsenoside Rd

CAS: 52705-93-8

Ref. TR-G387620

Product Information

• Name: Ginsenoside Rd
• Synonyms: ß-D-Glucopyranoside, (3ß,12ß)-20-(ß-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-ß-D-glucopyranosyl-, Dammarane, ß-D-glucopyranoside deriv., (3ß,12ß)-20-(ß-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-ß-D-glucopyranosyl-ß-D-glucopyranoside, 3-O-ß-D-Glucopyranosyl-(1?2)-ß-D-glucopyranosyl-20-O-ß-D-glucopyranosyldammar-24-ene-3ß,12ß,20S-triol, Chikusetsusaponin FK7, Ginsenoside Rd1, Gypenoside VIII, (3β,12β)-20-(β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside, (8xi,9xi,12alpha,13alpha,14beta,17beta)-17-[(1S)-1-(beta-D-glucopyranosyloxy)-1,3,5-trimethylhex-4-en-1-yl]-12-hydroxy-4,4,10,14-tetramethylgonan-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside, 2-O-beta-D-Glucopyranosyl-(3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-beta-D-glucopyranoside, 3-O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→2)-β-<smallcap>D</smallcap>-glucopyranosyl-20-O-β-<smallcap>D</span>-glucopyranosyldammar-24-ene-3β,12β,20S-triol, Chikusetsusaponin FK₇, Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv., Gold Theragran P.E., beta-D-Glucopyranoside, (3-beta,12-beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-, β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β)-20-(β-<smallcap>D</smallcap>-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-

Description

Stability Hygroscopic
Applications Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia.
References Zhang, X. et al.: Neurochem. Res., 39, 1363 (2014); Zhu, D. et al.: J. Neurosci. Res., 92, 1217 (2014);

• Brand: TRC

Chemical properties

• Molecular weight: 947.15
• Formula: C₄₈H₈₂O₁₈
• Color/Form: Neat
• InChI: InChI=1S/C48H82O18/c1-22(2)10-9-14-48(8,66-42-39(60)36(57)33(54)26(20-50)62-42)23-11-16-47(7)31(23)24(52)18-29-45(5)15-13-30(44(3,4)28(45)12-17-46(29,47)6)64-43-40(37(58)34(55)27(21-51)63-43)65-41-38(59)35(56)32(53)25(19-49)61-41/h10,23-43,49-60H,9,11-21H2,1-8H3/t23-,24+,25+,26+,27+,28-,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,45-,46+,47+,48-/m0/s1
• InChI key: InChIKey=RLDVZILFNVRJTL-IIBVISJDSA-N
• SMILES: CC(C)=CCCC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O[C@H]4OC(CO)[C@@H](O)C(O)C4O[C@@H]4OC(CO)[C@@H](O)C(O)C4O)C(C)(C)[C@@H]3CC[C@]12C