d-Glaucine

CAS: 475-81-0

Ref. TR-G406900

Product Information

• Name: d-Glaucine
• Synonyms: (6aS)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline, (6aS)-1,2,9,10-Tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline, (S)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline, (S)-Glaucine, 4H-Dibenzo[de,g]quinoline, 5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-, (S)-, 4H-dibenzo[de,g]quinoline, 5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-, (6aS)-, 6a.alpha.-Aporphine, 1,2,9,10-tetramethoxy-, 6aα-Aporphine, 1,2,9,10-tetramethoxy-, Boldine Dimethyl Ether, Bromcholitin, Glauvent, N,O,O′-Trimethyllaurelliptine, NSC 34396, O,O-Dimethylboldine, O,O-Dimethylisoboldine

Description

Applications d-Glaucine has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries.
References Cortijo, J., et al.: Brit. J. Pharm., 127, 1641 (1999); Rühle, K., et al.: Brit. J. Clin. Pharm., 17, 521 (1984)

• Brand: TRC

Chemical properties

• Molecular weight: 355.43
• Formula: C₂₁H₂₅NO₄
• Color/Form: Pale Yellow to Pale Beige Solid
• InChI: InChI=1S/C15H23NO2/c1-4-18-15(17)14(10-11-16(2)3)12-13-8-6-5-7-9-13/h5-9,14H,4,10-12H2,1-3H3
• InChI key: InChIKey=LVGYZCJPDTZCNY-UHFFFAOYSA-N
• SMILES: CCOC(=O)C(CCN(C)C)Cc1ccccc1