Glibornuride

CAS: 26944-48-9

Ref. TR-G409700

Product Information

• Name: Glibornuride
• Synonyms: Benzenesulfonamide, N-[[[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl]amino]carbonyl]-4-methyl-, Benzenesulfonamide, N-[[(3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl)amino]carbonyl]-4-methyl-, [1S-(endo,endo)]-, Urea, 1-(2-hydroxy-3-bornyl)-3-(p-tolylsulfonyl)-, (1R,2R,3S,4S)- (8CI), Gluboride, Glutril, Ro 6-4563, Ro 6-4563/8, endo, endo-1-[(1R)-(2-Hydroxy-3-bornyl)]-3-(p-tolylsulfonyl)urea, endo,endo-1-(2-Hydroxy-3-bornyl)-3-(p-tolylsulfonyl)urea, Benzenesulfonamide, N-[[(3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl)amino]carbonyl]-4-methyl-, [1S-(endo,endo)]-, Benzenesulfonamide, N-[[[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl]amino]carbonyl]-4-methyl-, N-[(3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl)carbamoyl]-4-methylbenzenesulfonamide, N-[[[(1S,2S,3R,4R)-3-Hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl]amino]carbonyl]-4-methylbenzenesulfonamide, Urea, 1-(2-hydroxy-3-bornyl)-3-(p-tolylsulfonyl)-, (1R,2R,3S,4S)-, endo, endo-1-[(1R)-(2-Hydroxy-3-bornyl)]-3-(p-tolylsulfonyl)urea

Description

Applications Glibornuride has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. Glibornuride is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mielsen-Kudsk, J.E., Thirstrup, S.: Pulm. Pharmacol., 6, 185 (1993); Bodmer, M., et. al.: Diabetes Care, 31, 2086 (2008)

• Brand: TRC

Chemical properties

• Molecular weight: 366.48
• Formula: C₁₈H₂₆N₂O₄S
• Color/Form: White To Off-White
• InChI: InChI=1S/C18H26N2O4S/c1-11-5-7-12(8-6-11)25(23,24)20-16(22)19-14-13-9-10-18(4,15(14)21)17(13,2)3/h5-8,13-15,21H,9-10H2,1-4H3,(H2,19,20,22)/t13-,14+,15+,18+/m1/s1
• InChI key: InChIKey=RMTYNAPTNBJHQI-OIPACUDHSA-N
• SMILES: Cc1ccc(S(=O)(=O)NC(=O)N[C@@H]2[C@@H](O)[C@@]3(C)CC[C@@H]2C3(C)C)cc1