Product Information
- (2?)-D-Glucoheptonic Acid ?-Lactone
- Glucoheptonic Acid ?-Lactone
- D-Glucoheptonolactone
- (3R,4S,5S)-3,4-dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]dihydrofuran-2(3H)-one (non-preferred name)
- (4S,5S)-3,4-dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]dihydrofuran-2(3H)-one (non-preferred name)
- <span class="text-smallcaps">D</span>-Glucoheptono-1,4-lactone
- <span class="text-smallcaps">D</span>-gluco-Heptonic acid, γ-lactone, (2ξ)-
- Glucoheptonic acid, γ-lactone
- alpha-D-Glucoheptonic gamma-lactone
- D-gluco-Heptonic acid, γ-lactone, (2ξ)-
- See more synonyms
Applications It is used in the synthesis of Howiinol A and its analogs. Howiinol A was one of the active antitumor constituents from the root and stem bark of Goniothamus howii (Annonaceae), and it was synthesized in 9 steps from α-D-glucoheptonic γ-lactone. Twenty-six analogs were also synthesized in searching for new antitumor compounds with high potency.
References Dhanvantari, S., et al.: J. Biol. Chem., 275, 29887 (2000), Kjellin, U., et al.: Langmuir, 17, 1941 (2001),
Chemical properties
Technical inquiry about: TR-G416500 D-Glucoheptono-1,4-lactone
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