Glyburide

CAS: 10238-21-8

Ref. TR-G598350

Product Information

• Name: Glyburide
• Synonyms: Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-, Urea, 1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexyl-, 1-[4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonyl]-3-cyclohexylurea, 1-[[-p-[2-(5-Chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexylurea, 1-[p-2-(5-Chloro-o-anisamido)ethylphenylsulfonyl]-3-cyclohexylurea, Abbenclamide, Adiab, Antibet, Apo-Glibenclamide, Azuglucon, Bastiverit, Benclamin, Betanase, Betanaz, Betanese 5, Calabren, Cytagon, Daonil, Daonil N, Debtan, Dia-basan, Diaben, Diabeta, Diabiphage, Dibelet, Duraglucon, Euglucan, Euglucon, Euglucon 5, Euglykon, GBN 5, Gilemal, Gl, Glamide, Gliban, Gliben, Gliben-Puren N, Glibenclamide, Glibenil, Glibens, Glibesyn, Glibet, Glibetic, Glibil, Gliboral, Glicem, Glidiabet, Glimel, Glimide, Glimidstada, Glisulin, Glitisol, Glubate, Gluben, Glucal, Gluco-Tabinen, Glucobene, Glucohexal, Glucolon, Glucomid, Glucoremed, Glucoven, Glukovital, Glyben, Glybenzcyclamide, Glycolande, Glycolande N, Glycomin, Glynase, HB 419, HD 419, Hemi-Daonil, Humedia, Libanil, Maninil, Med-Glionil, Melix, Micronase, Miglucan, N-4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonyl-N'-cyclohexylurea, N-[4-(b-(2-Methoxy-5-chlorobenzamido)ethyl)benzosulfonyl]-N'-cyclohexylurea, N-[4-[b-(2-Methoxy-5-chlorobenzamido)ethyl]benzenesulfonyl]-N'-cyclohexylurea, Norboral, Orabetic, Pira, Prodiabet, Renabetic, Semi-Daonil, Semi-Euglucon, Semi-Euglucon N, Sugril, Suraben, Tiabet, U 26452, UR 606, Wuglucon, Yuglucon, N-[4-(b-(2-Methoxy-5-chlorobenzamido)ethyl)benzosulfonyl]-N'-cyclohexylurea, N-[4-[b-(2-Methoxy-5-chlorobenzamido)ethyl]benzenesulfonyl]-N'-cyclohexylurea, 5-Chloro-N-(2-(4-((((Cyclohexylamino)Carbonyl)-Amino)Sulfonyl)Phenyl)-Ethyl)-2-Methoxybenzamide, 5-Chloro-N-(2-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenyl)ethyl)-2-methoxybenzamide, 5-chloro-2-methoxy-N-[2-[4-(phenylcarbamoylsulfamoyl)phenyl]ethyl]benzamide, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Amglidia, Diazet, Glibenclamid, Glibenclamida, Glibomet, Glicuformine, Glustat, Gluvans, Glybenclamide, Glyburine, Glyform, Glymet, N-[4-(β-(2-Methoxy-5-chlorobenzamido)ethyl)benzosulfonyl]-N'-cyclohexylurea, N-[4-[β-(2-Methoxy-5-chlorobenzamido)ethyl]benzenesulfonyl]-N'-cyclohexylurea

Description

Applications Glyburide is a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic.
References Mizukami, et al.: Arzneimittel-Forsch., 19, 1413 (1969); Efendic, S., et al.: Proc. Nat. Acad. Sci. USA, 76, 5901 (1979); Feldman, J.M.: Pharmacotherapry, 5, 43 (1985);

• Brand: TRC

Chemical properties

• Molecular weight: 494.00
• Formula: C₂₃H₂₈ClN₃O₅S
• Color/Form: Neat
• InChI: InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)
• InChI key: InChIKey=ZNNLBTZKUZBEKO-UHFFFAOYSA-N
• SMILES: COc1ccc(Cl)cc1C(=O)NCCc1ccc(S(=O)(=O)NC(=O)NC2CCCCC2)cc1