epi-Glycochenodeoxycholic Acid Sodium Salt-d7

CAS: 16564-43-5

Ref. TR-G641267

Product Information

• Name: epi-Glycochenodeoxycholic Acid Sodium Salt-d7
• Synonyms: N-[(3alpha,5beta,7alpha)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine Sodium Salt-d7, N-[(3alpha,5beta,7alpha)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine Monosodium Salt-d7, NSC 681056-d7, Sodium Chenodeoxycholylglycine-d7, Sodium Glycochenodeoxycholate-d7, Sodium Glycochenodesoxycholate-d7
• Brand: TRC

Description

Applications epi-Glycochenodeoxycholic Acid Sodium Salt-d7 is a labelled epimer analogue of Glycochenodeoxycholic Acid Sodium Salt (G641255), which is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005);

Chemical properties

• Molecular weight: 478.648
• Formula: C₂₆D₇H₃₅NNaO₅
• Color/Form: Neat
• InChI: InChI=1S/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/q;+1/p-1/t15-,16+,17+,18-,19+,20+,21-,24+,25+,26-;/m1./s1/i7D2,8D2,12D2,17D
• InChI key: InChIKey=AAYACJGHNRIFCT-ITXTXQEWSA-M
• SMILES: [2H]C([2H])(C[C@@H](C)[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@@]21C)[C@@]1(C)CC([2H])([2H])[C@]([2H])(O)C([2H])([2H])[C@H]1C[C@H]3O)C(=O)NCC(=O)O[Na]