Product Information
- 4-N,6-N-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine
- 4,6-Pyrimidinediamine, N,N′-dicyclopentyl-2-(methylthio)-5-nitro-
- 4,6-Pyrimidinediamine, N<sup>4</sup>,N<sup>6</sup>-dicyclopentyl-2-(methylthio)-5-nitro-
- 4,6-Pyrimidinediamine, N~4~,N~6~-dicyclopentyl-2-(methylthio)-5-nitro-
- Gs 39783
- N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine
- N<sup>4</sup>,N<sup>6</sup>-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine
Applications GS 39783 is an allosteric positive modulator of GABAB receptors. GS 39783 attenuates acute cocaine-induced hyperlocomotion and blocks cocaine-induced Fos induction in the striatal complex.
References Paterson, N. et al.: J. Pharmacol. Exp. Ther., 326, 306 (2008); Mombereau, C. et al.: J. Pharmacol. Exp. Ther., 321, 172 (2007); Lhuillier, L. et al.: Neuropsychopharmacol., 32, 388 (2007); Slattery, D. et al.: Neuropharmacol., 30, 2065 (2005)
Chemical properties
Technical inquiry about: TR-G797150 GS 39783
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