Estimated delivery in United States, on Monday 1 Jul 2024
Product Information
Name:
GSK 923295
Synonyms:
- 3-Chloro-N-{(1S)-2-[(N,N-dimethylglycyl)amino]-1-[(4-{8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl}phenyl)methyl]ethyl}-4-[(1-methylethyl)oxy]benzamide
- GSK 923295A
CAS:
Description:
Applications GSK 923295 is the first potent, CENP-E-selective inhibitor that has been tested in Phase I clinical trials for treatment of Refractory Cancers.
References Wood, K., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 5839 (2010); Qian, X., et al.: ACS Med. Chem. Lett., 1, 30 (2010); Lock, R., et al. Pediatr. Blood Cancer, 58, 916 (2012); Mayes, P., et al.: Int. J. Cancer, 132, E149 (2013)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
592.13
Formula:
C32H38ClN5O4
Color/Form:
Pale Yellow to Light Yellow Solid
InChI:
InChI=1S/C32H38ClN5O4/c1-20(2)42-29-13-12-24(16-27(29)33)32(41)35-25(17-34-30(40)19-37(4)5)15-22-8-10-23(11-9-22)28-18-38-14-6-7-26(21(3)39)31(38)36-28/h6-14,16,18,20-21,25,39H,15,17,19H2,1-5H3,(H,34,40)(H,35,41)/t21-,25-/m0/s1
InChI key:
InChIKey=WHMXDBPHBVLYRC-OFVILXPXSA-N
SMILES:
CC(C)Oc1ccc(C(=O)N[C@H](CNC(=O)CN(C)C)Cc2ccc(-c3cn4cccc([C@H](C)O)c4n3)cc2)cc1Cl
MDL:
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HS code:
Technical inquiry about: TR-G797750 GSK 923295
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