Product Information
Name:Guvacine Hydrochloride
Controlled Product
Synonyms:
- 1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Hydrochloride
- 1,2,5,6-Tetrahydro- nicotinic Acid Hydrochloride
Brand:TRC
Description:Applications Guvacine Hydrochloride is a GABA uptake inhibitor (hGABA T-1, rGABA T-2, hGABA T-3 and hBGT-1) (1,2,3). Gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain (4). Guvacine Hydrochloride may be useful for treating neuropsychiatric disorders.References (1) Lesnefsky, E., et al.: J. Biol. Chem., 279, 47961 (2004) (2) Nadtochiy, S., et al.: Biochem. J., 395, 611 (2006) (3) Corns, L.F., et al.: Neurosci Lett. 553, 57 (2013). (4) Borden, L. A., et al.: Eur J Pharmacol. 269, 219 (1994)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:163.60
Formula:C6H9NO2·ClH
Color/Form:Neat
InChI:InChI=1S/C6H9NO2.ClH/c8-6(9)5-2-1-3-7-4-5;/h2,7H,1,3-4H2,(H,8,9);1H
InChI key:InChIKey=FGNUNVVTHHKDAM-UHFFFAOYSA-N
SMILES:Cl.O=C(O)C1=CCCNC1
Technical inquiry about: Guvacine Hydrochloride
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