Product Information
Name:GW 1100
Controlled Product
Synonyms:
- 4-[5-[(2-Ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]benzoic Acid Ethyl Ester
- 1-(4-Ethoxycarbonylphenyl)-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone
Brand:TRC
Description:
Applications GW 1100 is a selective G protein-coupled receptor GPR40 antagonist. GW 1100 has been shown to reverse the effects GPR40 agonists which induce glucose-stimulated insulin secretion.
References Briscoe, C. et al.: Br. J. Pharmacol., 148, 619 (2006); Stoddart, L.A. et al.: Mol. Pharmacol., 71, 994 (2007);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:520.575
Formula:C27H25FN4O4S
Color/Form:Neat
InChI:InChI=1S/C27H25FN4O4S/c1-3-35-25(34)20-7-11-23(12-8-20)32-16-21(13-19-14-29-26(30-15-19)36-4-2)24(33)31-27(32)37-17-18-5-9-22(28)10-6-18/h5-12,14-16H,3-4,13,17H2,1-2H3
InChI key:InChIKey=PTPNCCWOTBBVJR-UHFFFAOYSA-N
SMILES:CCOC(=O)c1ccc(-n2cc(Cc3cnc(OCC)nc3)c(=O)nc2SCc2ccc(F)cc2)cc1
Technical inquiry about: GW 1100
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