Product Information
Name:GW 3965 Hydrochloride
Controlled Product
Synonyms:
- GW 3965A Hydrochloride
- 2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic Acid Hydrochloride
- 3-[3-[N-(2-Chloro-3-trifluoromethylbenzyl)(2,2-diphenylethyl)amino]propoxy]phenylacetic Acid Hydrochloride
- 3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-benzeneacetic Acid Hydrochloride
Brand:TRC
Description:Applications GW3965 Hydrochloride, is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXR. GW3965 has shown potent anti-inflammatory activity in both irritant and allergic contact models of dermatitis, requiring the participation of both LXRα and LXRβ.References Fowler, A.J., et. al.: J. Invest. Dermatol., 120, 246 (2003)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:582.053646
Formula:C33H31ClF3NO3•HCl
Color/Form:Neat
InChI:InChI=1S/C33H31ClF3NO3.ClH/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26;/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40);1H
InChI key:InChIKey=NMPUWJFHNOUNQU-UHFFFAOYSA-N
SMILES:Cl.O=C(O)Cc1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1
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