5'-​[Hydrogen P-​(1-​methyl-​1H-​imidazolium-​3-​yl)​phosphonate] 3'-​(2,​2,​2-​triacetate) 2'-​Deoxy-​2',​2'-​difluoro-​N-​(2,​2,​2-​trifluoroacetyl)​cytidine

CAS: 1035495-83-0

Ref. TR-H038595

Product Information

• Name: 5'-​[Hydrogen P-​(1-​methyl-​1H-​imidazolium-​3-​yl)​phosphonate] 3'-​(2,​2,​2-​triacetate) 2'-​Deoxy-​2',​2'-​difluoro-​N-​(2,​2,​2-​trifluoroacetyl)​cytidine
• Synonyms: [(2R,3R,5R)-4,4-difluoro-5-[2-oxo-4-[(2,2,2-trifluoroacetyl)amino]pyrimidin-1-yl]-3-(2,2,2-trifluoroacetyl)oxyoxolan-2-yl]methoxy-(3-methylimidazol-1-yl)phosphinate
• Brand: TRC
• Description: Applications 5'-​[Hydrogen P-​(1-​methyl-​1H-​imidazolium-​3-​yl)​phosphonate] 3'-​(2,​2,​2-​triacetate) 2'-​Deoxy-​2',​2'-​difluoro-​N-​(2,​2,​2-​trifluoroacetyl)​cytidine is an intermediate in the synthesis of Gemcitabine Triphosphate (G305020), which is a phosphorylated metabolite of Gemcitabine (G305000), an antineoplastic agent.References Kennedy., E.P., et al.: J. Biol. Chem., 222, 193 (1956),

Chemical properties

• Molecular weight: 599.283
• Formula: C₁₇H₁₄F₈N₅O₈P
• Color/Form: Neat
• InChI: InChI=1S/C17H15F8N5O8P/c1-28-4-5-29(7-28)39(34,35)36-6-8-10(38-13(32)17(23,24)25)15(18,19)12(37-8)30-3-2-9(27-14(30)33)26-11(31)16(20,21)22/h2-5,7-8,10,12H,6H2,1H3,(H,34,35)(H,26,27,31,33)/q+1/p-1/t8-,10-,12-/m1/s1