Product Information
Name:Harmine
Synonyms:
- 9H-Pyrido[3,4-b]indole
- 7-methoxy-1-methyl-
- 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole
- Banisterin
- Banisterine
- Harmin
- Leucoharmine
- Telepathin
- Telepathine
- Yagein
- Yageine
- 1-Methyl-7-methoxy-beta-carboline
- See more synonyms
Brand:TRC
Description:Applications Harmine is a natural β-carboline alkaloid and a CNS stimulant (1,2). Harmine has been shown to be a potent and selective inhibitor of dual specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A) (3). DYRK1A is a potential therapeutic target for treating diabetes, Down Syndrome, and HIV (4).References (1) DiStefano, S., et al.: J. Pharmacol. Exp. Ther., 174, 456 (1970)(2) Dos Santos, R. G. and Hallak, J. E. J Psychoactive Drugs. 5,1 (2016) (3) Atteya, R., et al.: Mech Ageing Dev. 6, S0047 (2016)(4) Bol, S. M., et al.: PLoS One. 6, e17190 (2011)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:212.25
Formula:C13H12N2O
Color/Form:White To Brown
InChI:InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
InChI key:InChIKey=BXNJHAXVSOCGBA-UHFFFAOYSA-N
SMILES:COc1ccc2c(c1)[nH]c1c(C)nccc12
Technical inquiry about: Harmine
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