Product Information
Name:6-Hydroxy-(S,S)-Palonosetron
Controlled Product
Synonyms:
- 6-Hydroxy Palonosetron
Brand:TRC
Description:Applications 6-Hydroxy-(S,S)-Palonosetron is an intermediate used in the synthesis of 6-Oxo-(S,S)-Palonosetron (O858568), which is an impurity of (S,S)-Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),
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Chemical properties
Molecular weight:312.41
Formula:C19H24N2O2
Color/Form:Neat
InChI:InChI=1S/C19H24N2O2/c22-17-5-4-13-10-21(16-11-20-8-6-12(16)7-9-20)19(23)15-3-1-2-14(17)18(13)15/h1-3,12-13,16-17,22H,4-11H2/t13-,16-,17?/m1/s1
InChI key:InChIKey=TZDXMUXWGXFPLG-ZIAVVELASA-N
SMILES:O=C1c2cccc3c2[C@H](CCC3O)CN1[C@@H]1CN2CCC1CC2
Technical inquiry about: 6-Hydroxy-(S,S)-Palonosetron
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