(3S,4S)-3-Hexyl-4-[(2R)-2-hydroxytridecyl]-2-oxetanone

CAS: 104872-06-2

Ref. TR-H296530

Product Information

• Name: (3S,4S)-3-Hexyl-4-[(2R)-2-hydroxytridecyl]-2-oxetanone
• Synonyms: 2-Oxetanone, 3-hexyl-4-(2-hydroxytridecyl)-, [3S-[3α,4β(S*)]]-, Orlistat Related Compound A (USP)
• Brand: TRC
• Description: Impurity Orlistat USP Related Compound AApplications (3S,4S)-3-Hexyl-4-[(2R)-2-hydroxytridecyl]-2-oxetanone (Orlistat USP Related Compound A) is an analog of Tetrahydrolipstatin, an inhibitor of the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG), also an intermediate in the preparation of Orlistat (O686500).References Mechoulam, R., et al.: Biochem. Pharmacol., 50, 83 (1995), Bisogno, T., et al.: J. Cell Biol., 163, 463 (2003), Di Marzo, V., et al.: Nat. Rev. Drug Discovery, 7, 438 (2008), Ortar, G., et al.: J. Med. Chem., 51, 6970 (2008),

Chemical properties

• Molecular weight: 354.57
• Formula: C₂₂H₄₂O₃
• Color/Form: Neat
• InChI: InChI=1S/C22H42O3/c1-3-5-7-9-10-11-12-13-14-16-19(23)18-21-20(22(24)25-21)17-15-8-6-4-2/h19-21,23H,3-18H2,1-2H3/t19-,20+,21+/m1/s1
• InChI key: InChIKey=RSOUWOFYULUWNE-HKBOAZHASA-N
• SMILES: CCCCCCCCCCC[C@@H](O)C[C@@H]1OC(=O)[C@H]1CCCCCC