N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycine

CAS: 1032564-18-3

Ref. TR-H296960

Product Information

• Name: N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycine
• Synonyms: 3-Hydroxy-1-adamantyl-D-glycine,2-((3-Hydroxyadamantan-1-yl)amino)acetic Acid
• Brand: TRC

Description

Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycine, is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase.
References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

Chemical properties

• Molecular weight: 225.28
• Formula: C₁₂H₁₉NO₃
• Color/Form: Neat
• InChI: InChI=1S/C12H19NO3/c14-10(15)6-13-11-2-8-1-9(3-11)5-12(16,4-8)7-11/h8-9,13,16H,1-7H2,(H,14,15)
• InChI key: InChIKey=FSZTVAMKEHAGGP-CDJYRKNRSA-N
• SMILES: O=C(O)CN[C@@]12C[C@@H]3C[C@@H](C[C@@](O)(C3)C1)C2