5-Hydroxy-7-methoxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one-d3

CAS: 532394-23-3

Ref. TR-H446716

Product Information

• Name: 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one-d3
• Synonyms: 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one-d3, WLH 163-d3
• Brand: TRC
• Description: Applications 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one-d3 is an intermediate for the synthesis of Alternariol Monomethyl Ether-d3 (A575771), labelled methyl este analog fo Alternariol. An alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing the rate of DNA strand breaks.References Asam, S., et al.: J. Agric. Food Chem., 57, 5152 (2009); Fehr, M., et al.: Mol. Nut. Food Res., 53, 441 (2009); Tiemann, U., et al.: Toxicol. Lett., 186, 139 (2009)

Chemical properties

• Molecular weight: 227.228
• Formula: C₁₁D₃H₉O₅
• Color/Form: Neat
• InChI: InChI=1S/C11H12O5/c1-11(2)15-8-5-6(14-3)4-7(12)9(8)10(13)16-11/h4-5,12H,1-3H3/i3D3
• InChI key: InChIKey=WFVAUGFNBVXHIW-HPRDVNIFSA-N
• SMILES: [2H]C([2H])([2H])Oc1cc(O)c2c(c1)OC(C)(C)OC2=O