rac Homatropine Hydrobromide

CAS: 51-56-9

Ref. TR-H459200

Product Information

• Name: rac Homatropine Hydrobromide
• Synonyms: Homatropine hydrobromide, (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2RS)-2-hydroxy-2-phenylacetate hydrobromide, Homatropine bromide, Isopto Homatropine, Mandelic acid tropine ester hydrobromide, 1αH,5αH-Tropan-3α-ol, mandelate (ester), hydrobromide (8CI), Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (9CI), Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide, endo-, (±)-Homatropine bromide, Homatropine hydrobromide, Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
• Brand: TRC

Description

Applications Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.
References Mattila, M.J. et al.: Ann. Med. Exp. Biol. Fen., 45, 412 (1967); Gambill, H. et al.: Arch. Ophthamol., 77, 740 (1967); Sund, R.B.: Med. Norsk Farmac. Sels., 33, 143 (1971);

Chemical properties

• Molecular weight: 356.25
• Formula: C₁₆H₂₁NO₃·BrH
• Color/Form: Neat
• InChI: InChI=1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H/t12-,13+,14+,15-;/m1./s1
• InChI key: InChIKey=PLNIOACITGBKQB-UHFFFAOYSA-N
• SMILES: Br.CN1[C@H]2CC[C@@H]1C[C@H](OC(=O)C(O)c1ccccc1)C2