Hydrocortisone(Cortisol)

CAS: 50-23-7

Ref. TR-H714615

Product Information

• Name: Hydrocortisone(Cortisol)
• Synonyms: Hydrocortisone, Cortisol, 11beta,17,21-Trihydroxy-pregn-4-ene-3,20-dione, Hydrocortisone Hydrogen Succinate Imp. A (EP), Prednisolone Imp. A (EP), Hydrocortisone Acetate Imp. A (Pharmeuropa), 17-Hydroxycorticosterone, Acticort, Aeroseb HC, Ala-Cort, Anflam, Anti-inflammatory hormone, CCN 90306A, CaldeCort Spray, Cetacort, Cobadex, Cort-Dome, Cortanal, Cortef, Cortenema, Corticreme, Cortifan, Cortiment, Cortispray, Cortonema, Cortril, Dermacort, Dermocortal, Dermolate, Dihydrocostisone, Dioderm, Domolene-HC, Efcorbin, Efcortelan, Eldecort, Epiderm H, Esiderm H, Evacort, Ficortril, Genacort, HC, Heb-Cort, Hidro-Colisona, Hycort, Hycortol, Hycortole, Hydracort, Hydrasson, Hydro-Adreson, Hydrocort, Hydrocortal, Hydrocorticosterone, Hydrocortisyl, Hydrocortone, Hydroskin, Hytone, Hytone lotion, Incortin-H, Kendall's compound F, Lacticare HC, Medicort, Mildison, NSC 10483, Nutracort, Optef, Otosone-F, Penecort, Permicort, Polcort H, Reichstein's substance M, Scheroson F, Signef, Synacort, Tarcortin, Texacort, Texacort lotion 25, Timocort, Topicort, Traumaide, U 1851, Zenoxone, Hydrocortisone, 11β,17,21-Trihydroxyprogesterone, 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 11β-Hydroxycortisone, 17α-Hydroxycorticosterone
• Brand: TRC
• Description: Impurity HYDROCORTISONE ACETATE EP IMPURITY AApplications Cortisol, or Hydrocortisone, a topical corticosteroid (1), more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis (3); suppress the immune system; and aid in fat, protein and carbohydrate metabolism.References 1. Vigore, L., et al.: Cancer Biol Ther. 2014 Jun 1;15(6):699-7062. Puurunen, J. et al.: J. Clin. Endocrinol. Metab. 2009 Jun;94(6):1973-8.3. Baltzegar, D. et al.: J Endocrinol. 2013 Nov 28;220(1):61-72.

Chemical properties

• Molecular weight: 362.46
• Formula: C₂₁H₃₀O₅
• Color/Form: Neat
• InChI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• InChI key: InChIKey=JYGXADMDTFJGBT-MKIDGPAKSA-N
• SMILES: C[C@]12C[C@@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO