Cortisol-9,12,12-d3

CAS: 115699-92-8

Ref. TR-H714624

Product Information

• Name: Cortisol-9,12,12-d3
• Synonyms: (11ß)-11,17,21-Trihydroxy-pregn-4-ene-3,20-dione-d3, Cortisol-d3, 11ß,17,21-Trihydroxypregn-4-ene-3,20-dione-d3, 17-Hydroxycorticosterone-d3, 17a-Hydroxycorticosterone-d3, NSC 10483-d3, (11ß)-11,17,21-Trihydroxypregn-4-ene-3,20-dione-9,12,12-d3, Hydrocortisone D3 (9,12,12 D3), Cortisol D3 (9,12,12 D3)

Description

Applications Isotope labelled Cortisol (H714615) a topical corticosteroid, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland . Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
References Vigore, L., et al.: Cancer Biol Ther.. 15. :699 (2014); Puurunen, J. et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009);

• Brand: TRC

Chemical properties

• Molecular weight: 365.48
• Formula: C₂₁D₃H₂₇O₅
• Color/Form: Neat
• InChI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1/i10D2,18D
• InChI key: InChIKey=JYGXADMDTFJGBT-NBMVOZGRSA-N
• SMILES: [2H]C1([2H])[C@H](O)[C@@]2([2H])C(CCC3=CC(=O)CC[C@@]32C)C2CC[C@](O)(C(=O)CO)[C@]21C