N-(4-Hydroxybenzyl)-3,4-dimethoxybenzamide

CAS: 943518-63-6

Ref. TR-H809755

Product Information

• Name: N-(4-Hydroxybenzyl)-3,4-dimethoxybenzamide
• Synonyms: N-[(4-hydroxyphenyl)methyl]-3,4-dimethoxybenzamide

Description

Applications N-(4-Hydroxybenzyl)-3,4-dimethoxybenzamide is an intermediate in the synthesis of Itopride (I931500, HCl); a dopamine D2-receptor antagonist with anticholinesterase activity. Also gastroprokinetic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Iwanaga, Y., et al; Jpn. J. Pharmacol., 56, 261 (1991); Mushiroda, T., et al.: Drug Metab. Dispos., 28, 1231 (2000); Khamar, B.M., et al.: PCT Int. Appl. WO 2007074386 A2 20070705. Jul 5, 2007

• Brand: TRC

Chemical properties

• Molecular weight: 287.31
• Formula: C₁₆H₁₇NO₄
• Color/Form: Neat
• InChI: InChI=1S/C16H17NO4/c1-20-14-8-5-12(9-15(14)21-2)16(19)17-10-11-3-6-13(18)7-4-11/h3-9,18H,10H2,1-2H3,(H,17,19)
• InChI key: InChIKey=PHBYSUZNPFHIIS-UHFFFAOYSA-N
• SMILES: COc1ccc(C(=O)NCc2ccc(O)cc2)cc1OC