Product Information
- 4-hydroxybenzene-1,3-dicarbonitrile
- 1,3-Benzenedicarbonitrile, 4-Hydroxy-
- 4-Hydroxyisophthalonitrile
- 2,4-Dicyanophenol
Applications 4-Hydroxy-1,3-benzenedicarbonitrile is used in the preparation of febuxostat (F229000), a non-purine xanthine oxidase inhibitor used as a treatment for hyperuricaemia and chronic gout.
References Smith, C.J., et al.: Bioorg. Med. Chem. Lett., 20, 346 (2010); Cramp. S., et al.: BIoorg. Med. Chem. Lett., 20, 2516 (2010); Sato, T., et al.: Bioorg. Med. Chem. Lett., 19, 184 (2009);
Chemical properties
Technical inquiry about: TR-H809760 4-Hydroxy-1,3-benzenedicarbonitrile
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