rac erythro-9-(2-Hydroxy-3-nonyl)adenine Hydrochloride Salt
CAS: 58337-38-5
Ref. TR-H825550
1mg | 151.00 € |
Product Information
- (2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol;hydrochloride
- (R*,S*)-(+-)-6-Amino-beta-hexyl-alpha-methyl-9H-purine-9-ethanol
- 9H-purine-9-ethanol, 6-amino-beta-hexyl-alpha-methyl-
- 9H-Purine-9-ethanol, 6-amino-beta-hexyl-alpha-methyl-, (R*,S*)-(+-)-
- 3-(6-Amino-9H-purin-9-yl)nonan-2-ol
Applications A potent inhibitor of phosphodiesterase II (PDE II) (IC50=800nM). Does not inhibit other PDE isozymes (IC50>100uM). Inhibits the retrograde transport motor, dynein. Also inhibits adenosine deaminase (Ki=4nM). Potent PDE-2 inhibitor.
References Lorbar, M., et al.: J. Mol. Cell. Cardiol., 31, 401 (1999), Verde, I., et al.: Br. J. Pharmacol., 127, 65 (1999),
Chemical properties
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