4-Hydroxy Atorvastatin Lactone-d5

CAS: 265989-49-9

Ref. TR-H828964

Product Information

• Name: 4-Hydroxy Atorvastatin Lactone-d5
• Synonyms: 1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-N-(4-hydroxyphenyl)-2-(1-methylethyl)-4-(phenyl-d5)-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]- (9CI), 5-(4-Fluorophenyl)-N-(4-hydroxyphenyl)-2-(1-methylethyl)-4-(phenyl-d5)-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide, (2R-trans)-5-(4-Fluorophenyl)-2-(1-methylethyl)-N-(4-hydroxyphenyl)-4-(phenyl-d5)-1-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)-ethyl]-1H-pyrrole-3-carboxamide, 4-Hydroxyatorvastatin lactone-d5, 4-Hydroxyatorvastatin lactone D5 (phenyl-D5), 4-Hydroxyatorvastatin-d5 δ-lactone, (4R,6R)-6-[2-[2-(4-Fluorophenyl)-4-(4-hydroxyphenylcarbamoyl)-5-(1-methylethyl)-3-(phenyl-d5)-1H-pyrrol-1-yl]ethyl]-4-hydroxytetrahydro-2H-pyran-2-one
• Brand: TRC
• Description: Applications A labelled metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

Chemical properties

• Molecular weight: 561.65
• Formula: C₃₃₂H₅H₂₈FN₂O₅
• Color/Form: Neat
• InChI: InChI=1S/C33H33FN2O5/c1-20(2)31-30(33(40)35-24-12-14-25(37)15-13-24)29(21-6-4-3-5-7-21)32(22-8-10-23(34)11-9-22)36(31)17-16-27-18-26(38)19-28(39)41-27/h3-15,20,26-27,37-38H,16-19H2,1-2H3,(H,35,40)/t26-,27-/m1/s1/i3D,4D,5D,6D,7D
• InChI key: InChIKey=KDJMDZSAAFACAM-GVULGNFTSA-N
• SMILES: [2H]c1c([2H])c([2H])c(-c2c(C(=O)Nc3ccc(O)cc3)c(C(C)C)n(CC[C@@H]3C[C@@H](O)CC(=O)O3)c2-c2ccc(F)cc2)c([2H])c1[2H]