10-Hydroxy Camptothecin

CAS: 19685-09-7

Ref. TR-H875000

Product Information

• Name: 10-Hydroxy Camptothecin
• Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (4S)-, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (S)-, Camptothecine, 10-hydroxy- (8CI), (+)-10-Hydroxycamptothecin, (S)-10-Hydroxycamptothecin, 10-Hydroxycamptothecin, 10-Hydroxycamptothecine, ChEMBL 273862, Hydroxycamptothecin
• Brand: TRC
• Description: Impurity Irinotecan USP Related Compound AApplications A Camptothecin derivative; a topoisomerase inhibitor for cancer therapy. Irinotecan USP Related Compound A Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986), Miller, K.D., et al.: Invest. New Drugs, 22, 69 (2004), Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (2004), Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (2005),

Chemical properties

• Molecular weight: 364.35
• Formula: C₂₀H₁₆N₂O₅
• Color/Form: Yellow
• InChI: InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1
• InChI key: InChIKey=HAWSQZCWOQZXHI-FQEVSTJZSA-N
• SMILES: CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(O)ccc3nc2-1