Estimated delivery in United States, on Thursday 23 Jan 2025
Product Information
Name:
4α-Hydroxy Cholesterol
Controlled Product
Synonyms:
- Cholest-5-ene-3,4-diol
- (3ß,4a)-
- Cholest-5-ene-3ß,4a-diol (8CI)
- (3ß,4a)-Cholest-5-ene-3,4-diol
- 4a-Hydroxycholesterol
- 3ß,4a-Dihydroxycholest-5-ene
- trans-3,4-Dihydroxy-?5-cholestene
- trans-?5-Cholestene-3,4-diol
- (3ß,4a)-Cholest-5-ene-3,4-diol
Description:
Applications A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.
References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
402.65
Formula:
C27H46O2
Color/Form:
Neat
InChI:
InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)20-11-12-21-19-9-10-23-25(29)24(28)14-16-27(23,5)22(19)13-15-26(20,21)4/h10,17-22,24-25,28-29H,6-9,11-16H2,1-5H3/t18-,19+,20-,21+,22+,24+,25+,26-,27-/m1/s1
InChI key:
InChIKey=CZDKQKOAHAICSF-GFYXKKFXSA-N
SMILES:
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4[C@H](O)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C
MDL:
Melting point:
Boiling point:
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Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-H917975 4α-Hydroxy Cholesterol
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