Product Information
- (3?,4?)-Cholest-5-ene-3,4-diol-d7
- Cholest-5-ene-3?,4?-diol-d7
- 3?,4?-Dihydroxycholest-5-ene-d7
- cis-3,4-Dihydroxy-5-cholestene-d7
- cis-5-Cholestene-3,4-diol-d7
Applications 4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.
References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),
Chemical properties
Technical inquiry about: TR-H917982 4β-Hydroxy Cholesterol-d7
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