(R,S)-4-Hydroxy Cyclophosphamide Preparation Kit

CAS: 61903-30-8

Ref. TR-H926301

Product Information

• Name: (R,S)-4-Hydroxy Cyclophosphamide Preparation Kit
• Synonyms: 2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2?^{5}-oxazaphosphinan-4-ol

Description

Stability Unstable in Solution
Applications A metabolite of Cyclophosphamide.This Kit consists of a vial of the precursor, 4-hydroperoxycyclophosphamide (H714675), and a vial of sodium thiosulfate (S673640). Simply add water to the reducing agent until it is completely dissolved and add this solution to the precursor. This solution has a half-life of approximately 200 minutes at room temperature. Detailed instructions are enclosed.
References Peter, G., et al.: Cancer. Chemother. Pharmacol., 3, 181 (1979), Fenselau, C., et al.: Drug Metab. Dispos., 10, 636 (1982), Gamcsik, M., et al.: J. Med. Chem., 33, 1009 (1990), Habib, A., et al.: Biochem. Pharmacol., 50, 429 (1995),

• Brand: TRC

Chemical properties

• Molecular weight: 277.09
• Formula: C₇H₁₅Cl₂N₂O₃P
• Color/Form: Off White Crystalline
• InChI: InChI=1S/C7H15Cl2N2O3P/c8-2-4-11(5-3-9)15(13)10-7(12)1-6-14-15/h7,12H,1-6H2,(H,10,13)
• InChI key: InChIKey=RANONBLIHMVXAJ-NZFNHWASSA-N
• SMILES: O=[P@]1(N(CCCl)CCCl)N[C@@H](O)CCO1