Product Information
Name:6-Hydroxy-L-DOPA
Controlled Product
Synonyms:
- 3-(3,4,6-Trihydroxyphenyl)-alanine
Brand:TRC
Description:Impurity Levodopa EP Impurity A; Levodopa USP Related Compound AStability HygroscopicApplications 6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.References Jaim-Etcheverry, G. et al.: Brain Res., 100, 699 (1975); Kostrzewa, R.M. et al.: Amino Acids, 14, 175 (1998); Berthet, A. et al.: J. Neurosci., 29, 4829 (2009);
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Chemical properties
Molecular weight:213.19
Formula:C9H11NO5
Color/Form:Brown To Black
InChI:InChI=1S/C9H11NO5/c10-5(9(14)15)1-4-2-7(12)8(13)3-6(4)11/h2-3,5,11-13H,1,10H2,(H,14,15)/t5-/m0/s1
InChI key:InChIKey=YLKRUSPZOTYMAT-YFKPBYRVSA-N
SMILES:N[C@@H](Cc1cc(O)c(O)cc1O)C(=O)O
Technical inquiry about: 6-Hydroxy-L-DOPA
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