Product Information
Name:2-Hydroxy-estrone-6-N3-adenine (90%)
Controlled Product
Synonyms:
- 6-(6-Amino-3H-purin-3-yl)-2,3-dihydroxy-estra-1,3,5(10)-trien-17-one
Brand:TRC
Description:Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:419.48
Formula:C23H25N5O3
Purity:90%
Color/Form:Neat
InChI:InChI=1S/C23H25N5O3/c1-23-5-4-11-12-7-17(29)18(30)8-14(12)16(6-13(11)15(23)2-3-19(23)31)28-10-27-21(24)20-22(28)26-9-25-20/h7-11,13,15-16,24,29-30H,2-6H2,1H3,(H,25,26)/t11-,13-,15+,16?,23+/m1/s1
InChI key:InChIKey=ILMIYAFNYQGIRH-RIGYJOQTSA-N
SMILES:C[C@]12CC[C@@H]3c4cc(O)c(O)cc4C(n4cnc(N)c5ncnc4-5)C[C@H]3[C@@H]1CCC2=O
Technical inquiry about: 2-Hydroxy-estrone-6-N3-adenine (90%)
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