Estimated delivery in United States, on Tuesday 14 Jan 2025
Product Information
Name:
2-Hydroxy-estrone-6-N3-adenine (90%)
Controlled Product
Synonyms:
- 6-(6-Amino-3H-purin-3-yl)-2,3-dihydroxy-estra-1,3,5(10)-trien-17-one
Description:
Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.
References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
419.48
Formula:
C23H25N5O3
Purity:
90%
Color/Form:
Neat
InChI:
InChI=1S/C23H25N5O3/c1-23-5-4-11-12-7-17(29)18(30)8-14(12)16(6-13(11)15(23)2-3-19(23)31)28-10-27-21(24)20-22(28)26-9-25-20/h7-11,13,15-16,29-30H,2-6,24H2,1H3/t11-,13-,15+,16?,23+/m1/s1
InChI key:
InChIKey=ILMIYAFNYQGIRH-RIGYJOQTSA-N
SMILES:
C[C@]12CC[C@@H]3c4cc(O)c(O)cc4C(n4cnc(N)c5ncnc4-5)C[C@H]3[C@@H]1CCC2=O
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-H942165 2-Hydroxy-estrone-6-N3-adenine (90%)
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