1-Hydroxy Fingolimod

CAS: 162361-49-1

Ref. TR-H942608

Product Information

• Name: 1-Hydroxy Fingolimod
• Synonyms: 1,4-Butanediol, 3-amino-3-(hydroxymethyl)-1-(4-octylphenyl)-, 3-Amino-3-(hydroxymethyl)-1-(4-octylphenyl)butane-1,4-diol

Description

Applications 1-Hydroxy Fingolimod, is an impurity of Fingolimod (F805000), an immunomodulating drug, mostly used for treating multiple sclerosis (MS). Fingolimod is also a sphingosine-1-phosphate receptor modulator, which sequesters lymphocytes in lymph nodes, preventing them from contributing to an autoimmune reaction.
References Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),

• Brand: TRC

Chemical properties

• Molecular weight: 323.47
• Formula: C₁₉H₃₃NO₃
• Color/Form: Neat
• InChI: InChI=1S/C19H33NO3/c1-2-3-4-5-6-7-8-16-9-11-17(12-10-16)18(23)13-19(20,14-21)15-22/h9-12,18,21-23H,2-8,13-15,20H2,1H3
• InChI key: InChIKey=XMWPVJOPHSHKHP-UHFFFAOYSA-N
• SMILES: CCCCCCCCc1ccc(C(O)CC(N)(CO)CO)cc1