(2S,4R)-4-Hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylic Acid tert-Butyl Ester

CAS:
61478-26-0

Ref. TR-H942835

Amino Acids (AA)

Product Information

Name:(2S,4R)-4-Hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylic Acid tert-Butyl Ester

Controlled Product

Synonyms:

(2S,4R)-tert-Butyl 4-Hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate
N-Boc-trans-4-hydroxy-L-prolinol
tert-Butyl (2S,4R)-4-Hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate
tert-Butyl (2S,4R)-4-Hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate

Brand:TRC

Description:

Applications A useful reactant used in the preparation of 4-purinylpyrrolidine nucleosides, kinase inhibitors and antibacterial agents.
References Abraham, S. et al.: Bioorg. Med. Chem. Lett., 21, 5296 (2011); Huang, X. et al.: Bioorg. Med. Chem. Lett., 19, 4130 (2009); Peterson, M. & Vince, R.: J. Med. Chem., 34, 2787 (1991)

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Chemical properties

Molecular weight:217.26

Formula:C₁₀H₁₉NO₄

Color/Form:Neat

InChI:InChI=1S/C10H19NO4/c1-10(2,3)15-9(14)11-5-8(13)4-7(11)6-12/h7-8,12-13H,4-6H2,1-3H3/t7-,8+/m0/s1

InChI key:InChIKey=UFJNFQNQLMGUTQ-SFYZADRCSA-N

SMILES:CC(C)(C)OC(=O)N1C[C@@H](O)C[C@@H]1CO

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