Product Information
- 1-(2-Chloroethyl)-3-(trans-4-hydroxycyclohexyl)-1-nitrosourea
- N-(2-Chloroethyl)-N'-(trans-4-hydroxycyclohexyl)-N-nitrosourea
- NSC 239717
- trans-4-Hydroxy CCNU
Applications trans-4-Hydroxy-lomustine is an impurity of lomustine (L469440) which is a chloroethylnitrosourea derivative with antitumor activity. Lomustine is similar to carmustine, chlorozotocin, nimustine, and ranimustine.
References Johnston, T.P., et al.: J. Med. Chem., 9, 892 (1966); Oliverio, V.T., et al.: Cancer Res., 30, 1330 (1970); Thompson, G.R., et al.: Toxicol. Appl. Pharmacol., 21, 405 (1972); Al-Shammary, F.J., et al.: Anal. Profiles Drug Subs., 19, 315 (1990)
Chemical properties
Technical inquiry about: TR-H942995 trans-4-Hydroxy-lomustine
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