4-Hydroxy-α1-[[[6-(1-methyl-3-phenylpropoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (Salmeterol Impurity)

CAS: 108928-81-0

Ref. TR-H948170

Product Information

• Name: 4-Hydroxy-α1-[[[6-(1-methyl-3-phenylpropoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (Salmeterol Impurity)
• Synonyms: 1,3-Benzenedimethanol, 4-hydroxy-α1-[[[6-(1-methyl-3-phenylpropoxy)hexyl]amino]methyl]-, 4-{1-Hydroxy-2-[6-(4-phenylbutan-2-yloxy)hexylamino]ethyl}-2-(hydroxymethyl)phenol, 1-[4-Hydroxy-3-(hydroxymethyl)-phenyl]-2-[[6-(1-methyl-3-phenylpropoxy)hexyl]-amino]ethanol, Salmeterol Related Compound B (USP), Salmeterol Xinafoate Imp. E (EP), GR 58583X, USP Salmeterol Related Compound B, Ph Eur Salmeterol Impurity E, GR 58583X
• Brand: TRC

Description

Applications 4-Hydroxy-α1-[[[6-(1-methyl-3-phenylpropoxy)hexyl]amino]methyl]-1,3-benzenedimethanol is an impurity of Salmeterol (S090100), a β2-Adrenergic agonist. Structural analog of Albuterol (A514500).
References Johnson, M.: Lung, 168, Suppl., 115 (1990), Ullman, A., et al.: Am. Rev. Resp. Dis., 142, 571 (1990), Twentyman, O.P., et al.: Lancet, 336, 1338 (1990)

Chemical properties

• Molecular weight: 415.57
• Formula: C₂₅H₃₇NO₄
• Color/Form: Neat
• InChI: InChI=1S/C25H37NO4/c1-20(11-12-21-9-5-4-6-10-21)30-16-8-3-2-7-15-26-18-25(29)22-13-14-24(28)23(17-22)19-27/h4-6,9-10,13-14,17,20,25-29H,2-3,7-8,11-12,15-16,18-19H2,1H3
• InChI key: InChIKey=QHJWMYXXRZALKR-UHFFFAOYSA-N
• SMILES: CC(CCc1ccccc1)OCCCCCCNCC(O)c1ccc(O)c(CO)c1