Product Information
Name:3-Hydroxy-2-naphthoic Acid-d6
Controlled Product
Synonyms:
- 1,4,5,6,7,8-hexadeuterio-3-hydroxynaphthalene-2-carboxylic acid
Brand:TRC
Description:Applications 3-Hydroxy-2-naphthoic Acid-d6 is an intermediate used in the synthesis of Pamoic Acid-d10 (P173502), which is a labelled Pamoic Acid. Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases. Enzyme replacement therapy in pancreatic enzyme deficiency.References Fonge H., et al.: Bioconjugate Chem., 18, 1924 (2007), Mayr, G.W., et al.: J. Biol. Chem., 282, 35424 (2007); Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010); Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009);
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Chemical properties
Molecular weight:194.216
Formula:C11D6H2O3
Color/Form:Neat
InChI:InChI=1S/C11H8O3/c12-10-6-8-4-2-1-3-7(8)5-9(10)11(13)14/h1-6,12H,(H,13,14)/i1D,2D,3D,4D,5D,6D
InChI key:InChIKey=ALKYHXVLJMQRLQ-MZWXYZOWSA-N
SMILES:[2H]c1c([2H])c([2H])c2c([2H])c(C(=O)O)c(O)c([2H])c2c1[2H]
Technical inquiry about: 3-Hydroxy-2-naphthoic Acid-d6
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