3Alpha-Hydroxy Pravastatin Lactone-d3

CAS: 1329809-35-9

Ref. TR-H952302

Product Information

• Name: 3Alpha-Hydroxy Pravastatin Lactone-d3
• Synonyms: 3α-iso-Pravastatin-d3, (2S)-2-(Methyl-d3)butanoic Acid (1S,6S,7R,8S,8aR)-1,2,6,7,8, 8a-Hexahydro-6-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester, SQ 31906 Lactone-d3
• Brand: TRC

Description

Applications A labelled metabolite of Pravastatin (P702000), a competitive inhibitor of HMG-CoA reductase.
References Serizawa, N., et al.: J. Antibiot., 36, 604 (1983), White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)

Chemical properties

• Molecular weight: 409.53
• Formula: C₂₃H₃₁D₃O₆
• Color/Form: Neat
• InChI: InChI=1S/C23H34O6/c1-4-13(2)23(27)29-20-7-5-6-15-10-19(25)14(3)18(22(15)20)9-8-17-11-16(24)12-21(26)28-17/h5-6,10,13-14,16-20,22,24-25H,4,7-9,11-12H2,1-3H3/t13?,14-,16-,17-,18+,19-,20+,22+/m1/s1/i2D3
• InChI key: InChIKey=JCXABYACWXHFQQ-JZMPFTGZSA-N
• SMILES: [2H]C([2H])([2H])C(CC)C(=O)O[C@H]1CC=CC2=C[C@@H](O)[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21