trans-4-Hydroxy-L-proline

CAS: 51-35-4

Ref. TR-H952376

Product Information

• Name: trans-4-Hydroxy-L-proline
• Synonyms: (4R)-4-Hydroxy-L-proline, L-Proline, 4-hydroxy-, trans-, Proline, 4-hydroxy-, L- (8CI), (4R)-4-Hydroxy-L-proline, (-)-4-Hydroxy-2-pyrrolidinecarboxylic acid, (2S,4R)-(-)-4-Hydroxyproline, (2S,4R)-4-Hydroxyproline, (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, (R)-4-Hydroxy-(S)-proline, (R)-4-Hydroxy-L-proline, (S)-Hydroxyproline, 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic acid, 4(R)-Hydroxyproline, 4-Hydroxy-(S)-proline, 4-Hydroxy-L-proline, 4-Hydroxyproline, 4-trans-Hydroxy-L-proline, Hydroxy-L-proline, Hydroxyproline, Hypro, L-4-Hydroxyproline, L-Hydroxyproline, L-Hypro, L-trans-4-Hydroxyproline, Ls-Hydroxyproline, NSC 46704, Proline, 4-hydroxy-, trans-4-Hydroxyproline, trans-L-4-Hydroxyproline, trans-L-Hydroxyproline, d-Hydroxyproline, (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, (2S,4R)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid, (2S,4R)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid, (4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline, (4R)-4-hydroxy-L-proline, (4R,2S)-Hydroxyproline, (R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline, 1-Hydroxyproline, 1-hydroxy-L-proline, 3-hydroxy-L-proline, 4-Hydroxy-<span class="text-smallcaps">L</span>-proline, 4-L-Hydroxyproline, 4-hydroxy-L-proline (trans), 4-trans-Hydroxy-<span class="text-smallcaps">L</span>-proline, <span class="text-smallcaps">L</span>-4-Hydroxyproline, <span class="text-smallcaps">L</span>-Hydroxyproline, <span class="text-smallcaps">L</span>-Hypro, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, (4R)-, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, trans-, <span class="text-smallcaps">L</span>-trans-4-Hydroxyproline, H-Hyp-OH, Hydroxy-<span class="text-smallcaps">L</span>-proline, Hydroxyproline, L-, L-4-Hydroxyprolin, L-4-hidroxiprolina, L-Proline, 4-hydroxy-, (4R)-, L-Proline, 4-hydroxy-, trans-, L_s-Hydroxyproline, Nsc 46704, Proline, 4-hydroxy-, Proline, 4-hydroxy-, <span class="text-smallcaps">L</span>-, Proline, 4-hydroxy-, L-, Trans-4-hydroxyl-L-proline, delta-Hydroxyproline, trans-(2S,4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline, trans-4-Hydroxy-<span class="text-smallcaps">L</span>-proline, trans-<span class="text-smallcaps">L</span>-4-Hydroxyproline, trans-<span class="text-smallcaps">L</span>-Hydroxyproline, δ-Hydroxyproline

Description

Applications A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.
References Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001);

• Brand: TRC

Chemical properties

• Molecular weight: 131.13
• Formula: C₅H₉NO₃
• Color/Form: Neat
• InChI: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
• InChI key: InChIKey=PMMYEEVYMWASQN-DMTCNVIQSA-N
• SMILES: O=C(O)[C@@H]1C[C@@H](O)CN1