cis-4-Hydroxy-L-proline-d3 (Major)

CAS: 618-27-9

Ref. TR-H952379

Product Information

• Name: cis-4-Hydroxy-L-proline-d3 (Major)
• Synonyms: cis-4-Hydroxy-L-proline-2,5,5-d3, (4S)-4-Hydroxy-L-proline-2,5,5-D3, cis-4-Hydroxy-L-proline-2,5,5-D3, (2S,4S)-4-Hydroxyproline-2,5,5-d3, (2S,4S)-4-Hydroxypyrrolidine-2,5,5-d3 acid, (2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid, (2S,4S)-4-Hydroxyproline, (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid, (4S)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline, (S)-allo-Hydroxyproline, 4(S)-Hydroxy-2(S)-pyrrolidinecarboxylic acid, 4-cis-Hydroxy-<span class="text-smallcaps">L</span>-proline, <span class="text-smallcaps">L</span>-Allohydroxyproline, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, (4S)-, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, cis-, <span class="text-smallcaps">L</span>-Proline, allo-hydroxy-, <span class="text-smallcaps">L</span>-allo-4-Hydroxyproline, <span class="text-smallcaps">L</span>-allo-Hydroxyproline, <span class="text-smallcaps">L</span>-cis-4-Hydroxyproline, H-Cis-Hyp-OH, NSC 206274, Proline, 4-allo-hydroxy-, Proline, 4-allo-hydroxy-, <span class="text-smallcaps">L</span>-, allo-4-Hydroxyproline, allo-<span class="text-smallcaps">L</span>-Hydroxyproline, allo-Hydroxy-<span class="text-smallcaps">L</span>-proline, cis-4-Hydroxy-<span class="text-smallcaps">L</span>-proline, cis-4-Hydroxyproline, cis-Hydroxyproline, L-Proline, 4-hydroxy-, cis-, L-Proline, 4-hydroxy-, (4S)-, (4S)-4-Hydroxy-L-proline, Proline, 4-allo-hydroxy-, L-

Description

Stability Hygroscopic
Applications cis-4-Hydroxy-L-proline-d3 is deuterium labelled cis-4-Hydroxy-L-proline (H952375). Hydroxyprolines are valuable chiral building blocks for organic synthesis of pharmaceuticals. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.
References Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol., 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001)

• Brand: TRC

Chemical properties

• Molecular weight: 134.15
• Formula: C₅D₃H₆NO₃
• Color/Form: Neat
• InChI: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1/i2D2,4D
• InChI key: InChIKey=PMMYEEVYMWASQN-SHLVEUKBSA-N
• SMILES: [2H]C1([2H])N[C@]([2H])(C(=O)O)C[C@@H]1O