16a-Hydroxy Progesterone

CAS: 438-07-3

Ref. TR-H952430

Product Information

• Name: 16a-Hydroxy Progesterone
• Synonyms: Pregn-4-ene-3,20-dione, 16-hydroxy-, (16a)-, Pregn-4-ene-3,20-dione, 16a-hydroxy- (8CI), (16a)-16-Hydroxypregn-4-ene-3,20-dione, 16a-Hydroxy-4-pregnene-3,20-dione, 16a-Hydroxy-?4-pregnene-3,20-dione, 16a-Hydroxyprogesterone, NSC 523249, NSC 53910, (16Alpha)-16-Hydroxypregn-4-Ene-3,20-Dione, (16Alpha,17Xi)-16-Hydroxypregn-4-Ene-3,20-Dione, (16α)-16-Hydroxypregn-4-ene-3,20-dione, 16α-Hydroxy-4-pregnene-3,20-dione, 16α-Hydroxy-Δ⁴-pregnene-3,20-dione, 16α-Hydroxyprogesterone, Pregn-4-ene-3,20-dione, 16-hydroxy-, (16α)-, Pregn-4-ene-3,20-dione, 16α-hydroxy-

Description

Stability Hygroscopic
Applications 16α-Hydroxyprrogesterone is a hydroxylated metabolite of Progesterone (P755900). 16α-Hydroxyprogesterone binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.
References Ikonen, M. et al.: Nature, 212, 716 (1966); Storbeck, K.-H. et al.: Mol. Cell. Endocrinol., 336, 92 (2011);

• Brand: TRC

Chemical properties

• Molecular weight: 330.46
• Formula: C₂₁H₃₀O₃
• Color/Form: Off-White
• InChI: InChI=1S/C21H30O3/c1-12(22)19-18(24)11-17-15-5-4-13-10-14(23)6-8-20(13,2)16(15)7-9-21(17,19)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17+,18-,19+,20+,21+/m1/s1
• InChI key: InChIKey=LOVNYFVWYTXDRE-RMWFXKKMSA-N
• SMILES: CC(=O)[C@H]1[C@H](O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C